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Types of radiation therapy for breast cancer : Difference between proton and photon radiation therapy for breast cancer.

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Presenter

Dr Sudha Sommappa

Consultant Radiation Oncologist

Abstract of Topic

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Types of Radiation Therapy for Breast Cancer:

Difference Between Proton and Photon Radiation Therapy

Dr. Sudha Sommappa

Radiation Therapy Types:

1.     Photon Radiation Therapy (Conventional Radiotherapy):

o    Uses high-energy X-rays or gamma rays (photons) to target and destroy cancer cells.

o    Widely available and commonly used in breast cancer treatment.

o    Penetrates tissues and deposits energy along the path, affecting both cancerous and some surrounding healthy tissue.

2.     Proton Radiation Therapy:

o    Uses charged particles (protons) that have a unique physical property called the Bragg peak, allowing precise energy deposition at a specific depth.

o    Minimizes radiation exposure to surrounding healthy tissues and critical organs like the heart and lungs.

o    Particularly beneficial for left-sided breast cancers or cases needing re-irradiation.

Key Differences:

Feature

Photon Therapy

Proton Therapy

Radiation Type

X-rays (photons)

Charged particles (protons)

Tissue Penetration

Passes through tissue, affecting tissues before and beyond tumor

Stops sharply at tumor site (Bragg peak)

Damage to Healthy Tissue

Higher exposure

Lower exposure

Side Effects

Potentially more heart/lung toxicity

Reduced risk of cardiac and pulmonary damage

Availability

Widely available

Limited availability, higher cost

Indications

Standard breast cancer cases

Complex cases, pediatric patients, re-irradiation, left-sided tumors

Conclusion:

Proton therapy offers a more targeted, tissue-sparing option, reducing collateral damage, especially critical in left-sided breast cancer. Photon therapy remains effective and widely used but with potentially higher exposure to adjacent organs.

 

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